Index: firmware/App/Modes/Prime.c
===================================================================
diff -u -raa7b1f5f68aae23c1c52b32658fcb625c29accfb -r29a10234d477b500dd2a07ab269d49bd18b221eb
--- firmware/App/Modes/Prime.c	(.../Prime.c)	(revision aa7b1f5f68aae23c1c52b32658fcb625c29accfb)
+++ firmware/App/Modes/Prime.c	(.../Prime.c)	(revision 29a10234d477b500dd2a07ab269d49bd18b221eb)
@@ -60,6 +60,8 @@
 #define STEADY_VOLUME_COUNT_SEC                             ( 10000 / LOAD_CELL_STEADY_VOLUME_SAMPLING_TIME )  ///< Counter must be greater than 10 seconds before steady volume is true.
 #define STEADY_VOLUME_TIME_DEADLINE_MS                      ( 55 * MS_PER_SECOND )                             ///< Time in msec for the steady volume deadline time out.
 
+#define ARTERIAL_PRESSURE_BUBBLE_CLEAR_MAX_MMHG             ( 200.0F )                                         ///< Maximum arterial pressure reading (in mmHg) for bubble clear.
+
 /// States of the treatment reservoir management state machine.
 typedef enum PrimeReservoirMgmt_States
 {
@@ -109,6 +111,7 @@
 static U32 noAirDetectedStartTime;                              ///< starting time when detecting no air.
 static U32 purgeAirTimeOutStartTime;                            ///< Starting time for purge air state time out.
 static U32 primeSalineDialyzerStartTime;                        ///< Starting time of priming saline dialyzer circuit.
+static U32 primeSalineDialyzerBubbleClearStartTime;             ///< Starting time of priming saline dialyzer bubble clear.
 static U32 primeDialysateDialyzerStartTime;                     ///< Starting time of priming dialysate dialyzer circuit.
 static U32 primeDialysateBypassStartTime;                       ///< Starting time of priming dialysate bypass circuit.
 static U32 steadyVolumeSamplingStartTime;                       ///< Load cell steady volume sampling interval starting time.
@@ -720,6 +723,7 @@
 
     primeSalineDialyzerTimeLimit = (U32)( ( ( dialyzerDialysateVolume * DIALYZER_VOLUME_SCALE_FACTOR + DIALYZER_DVI_PATH_VOLUME_ML ) * SEC_PER_MIN * MS_PER_SECOND ) / BLOOD_PUMP_FLOW_RATE_SALINE_DIALYZER_ML_MIN );
     primeSalineDialyzerStartTime = getMSTimerCount();
+    primeSalineDialyzerBubbleClearStartTime = getMSTimerCount();
 
     if ( TRUE == doesAlarmStatusIndicateStop() )
     {
@@ -740,8 +744,23 @@
  *************************************************************************/
 static HD_PRE_TREATMENT_PRIME_STATE_T handlePrimeSalineDialyzerState( void )
 {
+    static BOOL bubbleClearActive = FALSE;
+
     HD_PRE_TREATMENT_PRIME_STATE_T state = HD_PRIME_SALINE_DIALYZER_STATE;
 
+    // Close valve 4-5 times to create pressure to clear Dialyzer bubbles
+    if ( TRUE == didTimeout( primeSalineDialyzerBubbleClearStartTime, ( primeSalineDialyzerTimeLimit / 5 ) ) )
+    {
+        primeSalineDialyzerBubbleClearStartTime = getMSTimerCount();
+        setValvePosition( VDI, VALVE_POSITION_C_CLOSE );
+        bubbleClearActive = TRUE;
+    }
+    if ( ( TRUE == bubbleClearActive ) && ( getFilteredArterialPressure() > ARTERIAL_PRESSURE_BUBBLE_CLEAR_MAX_MMHG ) )
+    {
+        // Pressure max reached, release pressure
+        setValvePosition( VDI, VALVE_POSITION_A_INSERT_EJECT );
+        bubbleClearActive = FALSE;
+    }
     if ( TRUE == didTimeout( primeSalineDialyzerStartTime, primeSalineDialyzerTimeLimit ) )
     {
         state = HD_PRIME_RESERVOIR_TWO_FILL_COMPLETE_STATE;